Go down with all guns blazing / firing

Means to resist to the very end with all one’s vigour and resources; dates from the 18th century in this metaphoric sense, but in its literal sense, when it was first used to describe a desperate naval or military engagement, it dates from at least the 1500s. Sometimes 'all guns blazing' is used on its own, metaphorically, and means simply with utmost vigour and forcefulness.